A gel made from a substance based on the cannabis plant could be an unlikely new treatment for sore knees.The clear, odourless gel, named ZYN002, is a synthetic form of a compound in the plant. It is rubbed on the front and back of the knee twice a day. The drug is thought to work by blocking receptors involved in transmitting Arthritis Pain signals to the brain.It is currently undergoing trials on 450 patients in the U.S., and initial tests suggest it can soothe the agony of osteoarthritis of the knee.
An estimated nine million people in Britain have some degree of osteoarthritis. As the body ages, the joints suffer wear and tear. Other risk factors include being overweight, a family history of the condition and sports injuries.As the cushioning cartilage in the joints breaks down, the bones come into contact with each other, causing inflammation and Arthritis Pain.Patients often rely on anti-inflammatory painkillers to ease their symptoms. While these help, they can damage the stomach if used for long periods.Steroid injections can dampen down inflammation but these sometimes worsen the condition by causing cortisone flare — where the injected steroid (cortisone) crystallises inside the joint and triggers more inflammation.