Greater Risk Of Skin Cancer In Inflammatory Bowel Disease Patients

These results suggest that people with In Inflammatory Bowel Disease may have an increased risk of nonmelanoma skin cancer, particularly if they use thiopurines.People with Inflammatory Bowel Disease are advised to protect their skin from the sun and monitor their skin of other changes.Researchers at the University of Dundee have found that skin cancers in mice can closely mirror those found in humans, offering a model that could be used to help develop new drugs to fight the disease.Skin cancer is the most common cancer worldwide and is on the rise.In the 10-year period from 2001 to 2011, Scotland saw an increase of more than 50 per cent in the incidence of the disease with around 3,000 new cases now diagnosed annually.

In many cases skin cancers can be removed but they are still a major cause of morbidity and mortality, especially in certain high-risk populations, including In Inflammatory Bowel Disease patients.“There is an urgent need to find an effective method for prevention and treatment, but suitable preclinical models have not been available,” said Albena Dinkova-Kostova, professor of Chemical Biology in the University’s Medical School.“We have developed a new preclinical model of UVR-induced skin cancer.